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Effects of Wolffia Globosa in Patients Undergoing Bariatric Surgery

October 23, 2019


This study is assessing the effects of using Wolffia Globosa (Mankai), a plant based wholesome food, as a replacement for the current high protein liquid diet given to pre- and post-operative bariatric surgery patients. Participants will be randomly divided into two groups; the first will receive three traditional shakes, and the second group will receive two traditional shakes and one daily administration of substituting iso-protein green Wolffia Globosa (Mankai) Shake. 


Study Information

This is a randomized, interventional study with approximately 120 participants. Investigators will collect anthropometric and clinical data on all patients, including blood samples collected at 2 weeks pre operatively, surgery day and at 2 months postoperatively. The study began on August 1st 2019 and is estimated to be completed on March 1st 2020. 


Inclusion Criteria

  • Patients that will undergo sleeve gastrectomy.


Exclusion Criteria

  • Age below 18 years
  • American Society of Anesthesiologist (ASA) class IV or V
  • Patients using Vitamin-K antagonists
  • Patients with documented coagulopathies



This clinical trial is taking place at the Cleveland Clinic Florida, Weston, Florida, United States, 33331. For further information or to participate, please contact Emanuele Lo Menzo, MD on 9546595232 or at


Sponsors / Collaborators

This study is sponsored by the Cleveland Clinic, with Emanuele Lo Menzo, MD as the Principal Investigator.

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